“Dr.” Mohammed Oz hasn’t learned from his stint in front of the senate. He recently raved about this product making claims such as:
NEW YORK, Nov.13, 2012 /PRNewswire/ — If you’ve been trying in vain find to find the anti-aging breakthrough everyone’s been talking about, SeroVital-hgh, you can blame Dr. Oz. He’s become well known for creating a firestorm of demand for products when he features the research behind them on his show. So when he told viewers about a revolutionary new way to potentially “stave off the aging process” and asked, “How many of you want to start feeling 20 years younger right now?” people everywhere paid attention.
Dr. Oz talked about the significance of human growth hormone, or HGH, calling it “fundamentally important to us staying youthful and vital.”
He said, “Now there’s a new frontier: stimulating your body’s production of growth hormones naturally with amino acids.”
Here is a link to the episode where he makes the claim:
Where’s the Research?
SeroVital manufacturers like to quote a 2012 study featuring “more than 500 of the most highly respected scientists from around the globe.” The study was presented and discussed at the Obesity Society’s 30th Annual Scientific meeting.
According to the study, the orally administered compound was “capable of increasing mean serum (blood) growth hormone levels by 682%.”
Sounds pretty convincing right?
For such a groundbreaking discovery, I can’t help but question its validity. If SeroVital could really increase HGH that dramatically, wouldn’t the study be published in a peer-reviewed journal?
Yet for all my searching, I can’t find the study anywhere online.
Secondly, I don’t know the exact ingredient concentrations in either the study or the formula. This means it’s impossible to tell if SeroVital produces the same results as the compound found in the study.
Furthermore, I don’t know who sponsored the study. Did SeroVital manufacturers create the study specifically to sell the product? Were the results slanted in the product’s favor?
Until more of my questions are answered, I’m not convinced SeroVital is as incredible as everyone seems to believe.
ANOTHER ARTICLE SAYS THIS:
Last week, TA from New York sent me a question about a supplement designed to boost growth hormone (GH) levels.
“Have you heard about a growth hormone stimulator named SeroVital?” she wrote. “Is it any good or the usual hype?”
According to the website, SeroVital is “an affordable oral formula that encourages the pituitary gland to increase growth hormone production at a more youthful rate, naturally, without dangerous drugs or synthetic hormone injections.”
What sort of results can you expect from injectable GH? And do growth hormone stimulators like SeroVital deliver the same benefits at a fraction of the cost?
In 1990, a huge amount of excitement was generated from research published in the New England Journal of Medicine describing the dramatic effects of growth hormone treatment in a small group of men.
The men (aged between 61 and 81) were treated with injections of human growth hormone three times a week for six months. The injections were sufficient to increase the men’s growth hormone levels to those of a normal person aged 20 to 40 years.
The volunteers gained around 10 pounds of lean body mass, and lost almost eight pounds of fat. Bone mineral density also increased. Growth hormone treatment also produced thicker, less wrinkled, younger-looking skin. In fact, skin thickness was restored to a level typically seen in a 50-year-old.
Even younger men and women appear to benefit. In one study, growth hormone led to a 12% decrease in body fat and a 4% increase in lean mass in a group of exercising men and women aged 22 to 33 years.
GH injections have also been shown to increase collagen (connective tissue) synthesis in muscle and tendon. This ties in with the experience of some athletes, who report that GH seems to help their injuries heal more quickly.
As I mentioned earlier, some trials also show an increase in skin thickness, which might explain why the guy I was speaking to at the gym the other day told me that using GH got rid of some of the lines on his face.
All of this talk about GH increasing lean mass might sound very exciting. But it’s only half the story.
Firstly, an increase in lean body mass doesn’t automatically mean more muscle.
In one study, a group of 16 men (aged 21-34) was assigned to a strength training + GH group or a strength training + placebo group. While GH injections led to an increase in fat-free mass, they had no effect on musclemass. To quote the researchers directly:
Fat-free mass (FFM) and total body water increased in both groups but more in the GH recipients. In the young men studied, resistance exercise with or without GH resulted in similar increments in muscle size, strength, and muscle protein synthesis, indicating that 1) the larger increase in FFM with GH treatment was probably due to an increase in lean tissue other than skeletal muscle and 2) resistance training supplemented with GH did not further enhance muscle anabolism and function.”
GH did lead to an increase in whole body protein synthesis. But there was no increase in muscle protein synthesis.
Muscle contributes only 25-30% to whole body protein synthesis. This means that protein turnover measured at the whole body level may or may not be indicative of what’s happening to muscle proteins.
Measuring protein turnover at the whole body level tells you that protein is being synthesized and stored, but it doesn’t tell you where.
As the researchers point out, the increase in lean mass was not due to an increase in muscle mass. It was more likely to be water retention, or growth in tissues other than muscle, such as the kidneys.
So even if SeroVital could replicate the effects of growth hormone injections (and it doesn’t, because if it did nobody would bother with injections), GH isn’t a particularly effective drug for muscle growth anyway.
It does have some benefits in terms of body composition, but it’s used mainly to augment the effects of other drugs, such as testosterone.
As far as supplements go, there is research to show that large oral doses of some amino acids elevate growth hormone levels.
But the increase in growth hormone is short-lived, relatively small and has not been shown to do a single thing for muscle growth or fat loss.
In short, most growth hormone stimulators are a complete waste of money. I’d highly recommend that you avoid them. http://muscleevo.net/growth-hormone-supplements/#.VAc_mtK-3To
I too was duped, I would have thought twice if I had known Dr. Mohammed Oz was the original source but my room mate brought up the subject and suggested we try it. I WANT MY 100$ BACK “DR.” OZ!!! Unlike most people placebos don’t work on me psychosomatic-ally, that is why homeopathy doesn’t work on me because it is the “science” of placebos. I took the pills just as i was supposed to and I noticed absolutely no difference. I have since then started supplementing amino acids and I do notice a difference with those. As far as I know there are approximately 9 amino acids that your body needs to get externally because they aren’t part of the diet and your body can’t manufacture them.
An essential amino acid or indispensable amino acid is an amino acid that cannot be synthesized de novo (from scratch) by the organism being considered, and therefore must be supplied in its diet. The nine amino acids humans cannot synthesize are phenylalanine, valine, threonine, tryptophan, methionine, leucine,isoleucine, lysine, and histidine.
Six amino acids are considered conditionally essential in the human diet, meaning their synthesis can be limited under special pathophysiological conditions, such as prematurity in the infant or individuals in severe catabolic distress. These six are arginine, cysteine, glycine, glutamine, proline and tyrosine. Five amino acids are dispensible in humans, meaning they can be synthesized in the body. These five are alanine, aspartic acid, asparagine, glutamic acid and serine. http://en.wikipedia.org/wiki/Essential_amino_acid